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Year : 2018  |  Volume : 19  |  Issue : 2  |  Page : 65-72

Controlled comparison between betamethasone gel and lidocaine jelly applied over endotracheal tube in reducing postoperative sore throat, cough, and hoarseness of voice

Department of Anesthesiology and Critical Care, Jaipur Golden Hospital, New Delhi, India

Correspondence Address:
Dr. Nitish Upadhyay
B-5/334-335, First Floor, Sector 3, Rohini, New Delhi - 110 085
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/TheIAForum.TheIAForum_30_18

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Background and Aims: Postoperative sore throat (POST), cough (C), and hoarseness of voice (H) are common, uncomfortable, and frequently ignored sequel after endotracheal intubation. They are likely to be the consequences of local irritation and inflammation so may be amenable to locally administered steroids. Systemic corticosteroids have been shown to prevent the postextubation upper airway obstruction after long-term intubation. Various reports about the efficacy of pharmacological and nonpharmacological measures on complications of intubation have been published. Materials and Methods: A prospective, randomized, hospital-based experimental study including 180 patients (American Society of Anesthesiologists physical status I and II; age group 18–45 years; and scheduled for elective surgery requiring general endotracheal anesthesia were randomly allocated into three groups – Group I, II, and C). Incidence and severity of POST, C, and H were compared using betamethasone gel, lignocaine jelly, or when nothing was applied. Incidence of coughing or bucking and hemodynamic variability was also compared between groups. Quantitative variables in various groups were expressed as mean ± standard deviation and compared using ANOVA and/or unpaired t-test between the groups and paired t-test within each group. Qualitative variables were expressed as frequencies/percentages and compared using Chi-square test. Results: Incidence and severity of POST, C, H, and coughing/bucking was maximum in Group C, followed by Group II and least in Group I (P < 0.05). Conclusion: Betamethasone gel applied over tracheal tube effectively reduces the incidence and severity of POST, C, and H as compared to lignocaine jelly or when nothing was applied.

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